ZDHHC20
ZDHHC20 (Zinc Finger DHHC-Type Palmitoyltransferase 20): ZDHHC20 is an enzyme belonging to the DHHC family of palmitoyltransferases. These enzymes catalyze protein palmitoylation, a post-translational modification where a fatty acid, palmitate, is attached to specific cysteine residues on target proteins. This modification regulates the proteins’ cellular localization, stability, and function. ZDHHC20 specifically facilitates the palmitoylation of certain proteins, affecting their membrane association and intracellular trafficking. Through this role, ZDHHC20 influences key cellular processes such as signal transduction, synaptic plasticity, and membrane trafficking. Dysregulation of ZDHHC20 has been linked to various neurological disorders.
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