TCF12
TCF12 (Transcription Factor 12): TCF12 is a member of the basic helix-loop-helix (bHLH) transcription factor family, involved in regulating gene expression during development and cell differentiation. TCF12 plays a key role in nervous system and muscle tissue development, influencing cell fate decisions and tissue formation. Mutations in TCF12 are associated with craniosynostosis, a condition marked by the premature fusion of skull bones, highlighting its importance in craniofacial development. Studying TCF12 provides valuable insights into developmental biology and the genetic basis of congenital disorders.
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