MYH11 (Myosin Heavy Chain 11): MYH11 is a gene that encodes a smooth muscle myosin heavy chain, a vital part of the contractile machinery in smooth muscle cells. This protein is essential for smooth muscle contraction and relaxation, supporting key functions like vascular regulation, gastrointestinal movement, and respiratory activity. MYH11 helps maintain the structure and function of smooth muscle tissues throughout the body. Changes or mutations in this gene can contribute to vascular disorders, including thoracic aortic aneurysms and dissections.